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Glucovance (Glyburide and Metformin) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Overview Glucovance is a prescription drug approved by the Food and Drug Administration (FDA) to help improve blood glucose control in adults with type 2 diabetes. Glucovance is considered an adjunct treatment to diet and exercise. Glucovance is a combination drug composed of the drugs Glyburide, the active ingredient in DiaBeta, and Metformin. Blink Health Online Pharmacy & Discount Prescriptions Generic name: Glyburide, Metformin Glucovance, glyburide, metformin, full prescribing information What is Glucovance and why is Glucovance prescribed? Glucovance is used in the treatment of type 2 (noninsulin dependent) diabetes. Diabetes develops when the body's ability to burn sugar declines and the unused sugar builds up in the bloodstream. 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