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Learn how the Xifaxan coupon, Xifaxan savings card, and other tools can help you save. Compare Xifaxan prices, print discount coupons, find manufacturer promotions, copay cards and patient assistance programs. Save on Rifaximin in 2026: compare pharmacy prices, find coupons, and discover discount programs. Medfinder helps you find the lowest price near you. Without assistance, Xifaxan costs hundreds of dollars or more per month at retail pharmacies. Discount programs offer some relief, but they don't come close to what a Patient Assistance Program provides, if you qualify: Xifaxan is prescribed to treat certain types of diarrhea and to lower the risk of a brain condition in adults with severe liver disease. It's a brand-name drug, available as the generic medication rifaximin. It comes as an oral tablet. The cost with or without insurance can depend on several factors. It might be lowered by using a coupon. 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XIFAXAN ® (rifaximin) 550 mg tablets are indicated for the reduction in risk of overt hepatic encephalopathy (HE) recurrence in adults and for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults. Get the best price on Rifaximin at pharmacies near you with SingleCare. Save up to 80% with our Rifaximin coupons – with or without insurance! XIFAXAN ® (rifaximin) 550 mg tablets are indicated for the reduction in risk of overt hepatic encephalopathy (HE) recurrence in adults and for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults. Get the facts on cost and Xifaxan, how the generic compares with the brand name, what financial assistance may be available, and more. Rifaximin Coupons & Savings Card – Discount Prices from $772.70 Generic for: Xifaxan Rifaximin, marketed under the name Xifaxan, is an antibiotic used primarily to treat diarrhea caused by E. coli, often referred to as "traveler's diarrhea," in individuals aged 12 and older. Ask PharmacyChecker: Q: How to Access Affordable Xifaxan (rifaximin) A: Xifaxan is a very popular medication and the pharmaceutical industry is cashing in. The average retail price for 60 Xifaxan 550 mg tablets sold at U.S. pharmacies is $3,271.84 – a steep 22% increase from the average price in 2019 ($2,686.95). Medicare spent over $844 million on Xifaxan in the year Medicare coverage and pricing details for Xifaxan. Learn more about Medicare prescription drug plans and savings with GoodRx. Learn about our Xifaxan patient assistance program, and apply today. APPLY NOW What Is Xifaxan? Xifaxan is used to treat irritable bowel syndrome with diarrhea (IBS-D) as well as the diarrhea often referred to as "traveler's diarrhea," which is caused by E. coli bacteria. Find the lowest price for Xifaxan with our free prescription discount coupon. Save up to 80% by comparing prices at major pharmacies. Medicare prescription drug plans usually cover Xifaxan. 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